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KMID : 1123820070090020041
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Health & sports medicine
2007 Volume.9 No. 2 p.41 ~ p.48
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Kim Ki-Jin
Ahn Na-Young
Hong Chang-Bae
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Abstract
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The purpose of the present study is to examine the effect of visceral obesity on metabolic syndrome. Obesity leads to risk factors of metabolic syndrome such as hyperlipidemia, hypertention, and insulin resistance, and also drives the progression of atherosclerosis and type 2 diabetes. It has recently been reported the hypoadiponectinemia together with the increase of adipokines induced by the accumulation of visceral obesity. Furthermore, the inflammation markers (increase CRP, IL-6, and TNF-α concentration), inflammation signal pathway (activity JNK, IKK-β, and NF-κB) and the metabolic syndrome (hyperlipidemia, atherosclerosis, hypertention and type 2 diabetics) are activated by visceral obesity. Therefore, the intervention of inflammation through decrease of visceral fat is important process for the inhibition of insulin resistance and atherosclerosis.
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KEYWORD
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visceral obesity, metabolic syndrome, inflammation marker
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